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Index > Protein center > Corin(Gene name) > Rat
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  • Corin (Gene name),
  • Atrial natriuretic peptide-converting enzyme (Protein name ),  CORIN_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Corin;
    Protein name:
    Atrial natriuretic peptide-converting enzyme;
    Alternative:
    Pro-ANP-converting enzyme;Corin;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Serine-type endopeptidase involved in atrial natriuretic peptide hormone processing. Converts through proteolytic cleavage the non-functional propeptide NPPA/ANP into the active hormone which promotes natriuresis, diuresis, and vasodilatation. May also process pro-NPPB the B-type natriuretic peptide.
    Subcellular Location:
    Cell membrane Single-pass type II membrane protein
    Protein Attributes:
    Sequence length:
    1111
    Sequence:
    50:
    MGRVSFNVRV | SSVRRARCSC | PGRCYLSCRV | PPTTALHALN | GFGRAGVLGE | 
    100:
    TAGGTVGLGP | SGTRGFLSGS | KFQASGSLKD | CFGAPPAPDV | LRADSSVGEG | 
    150:
    CPQKLVTANL | LRFLLLVLIP | CICALIVLLA | ILLSFVGTLK | KVYFKSNDSE | 
    200:
    PLVTDGEVRV | PGVIHVNRYE | NTGAPSMSPS | QSIPAWTPRA | PSLEDQSHGN | 
    250:
    TSTCVNITHR | QCQILPYHST | LAPLLPIVKN | MDTEKFLKFF | TYLHRLGCYQ | 
    300:
    HILLFGCSLA | FPKCIVDGDD | RHGLLPCRSF | CEAAKEGCES | VLGMVNSSWP | 
    350:
    DSLRCSQFRY | HTENNSDAST | ICFSLQQEHG | KQSLCGGGES | FLCTSGLCIS | 
    400:
    KKLQCNGYND | CDDWSDEAHC | NCSEDLFHCG | TGKCLHHSLV | CDGYDDCGDL | 
    450:
    SDEQNCDCNL | TKEHRCGDGR | CIAAEWVCDG | DHDCVDKSDE | VNCSCPSQGL | 
    500:
    VECRSGQCIP | STFQCDGDED | CKDGSDEENC | SDRPTPCPGG | DRGCLDSSCV | 
    550:
    ESCAGSSLCD | SDSSLSNCSH | CEPITLELCM | NLPYNLTHYP | NYLGHRTQKE | 
    600:
    ASISWESALF | PALVQTNCYK | YLMFFACTIL | VPKCDVNTGQ | RVPPCRLLCE | 
    650:
    HSKERCESVL | GIVGLQWPED | TDCSQFPEQS | SDNQTCLLPN | EDVEECSPSH | 
    700:
    FKCRSGRCVL | GSRRCDGQAD | CDDDSDEENC | GCKERDLWEC | PLNKQCLKHT | 
    750:
    LICDGFPDCS | DSMDEKNCSF | CQDDELECAN | HECVPRDLWC | DGWTDCSDSS | 
    800:
    DEWGCVTLSK | NGNSSSFLTV | HRSARDHHVC | ADGWQETLSQ | LACRQMGLGE | 
    850:
    PSVTELVQGQ | EGQQWLRLHS | SWENLNGSTL | QELLVHRRSC | PSGSEISLLC | 
    900:
    TKQDCGRRPA | ARMNKRILGG | RTSRPGRWPW | QCSLQSEPSG | HICGCVLIAK | 
    950:
    KWVLTVAHCF | EGREDADVWK | VVFGINNLDH | PSGFMQTRFV | KTILLHPRYS | 
    1000:
    RAVVDYDISV | VELSDDINET | SYVRPVCLPS | PREFLEPDTY | CYITGWGHMG | 
    1050:
    NKMPFKLQEG | EVRIIPLEQC | QSYFDMKTIT | NRMICAGYES | GTVDSCMGDS | 
    1100:
    GGPLVCERPG | GQWTLFGLTS | WGSVCFSKVL | GPGVYSNVSY | FVDWIERQIY | 
    1111:
    IQTFLQKKSQ | G
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Atrial natriuretic peptide-converting enzyme
    Cat.:
    E1930m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat Atrial natriuretic peptide-converting enzyme
    Cat.:
    E1930h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Rat Atrial natriuretic peptide-converting enzyme
    Cat.:
    E1930r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Atrial natriuretic peptide-converting enzyme
    Cat.:
    U1930r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Atrial natriuretic peptide-converting enzyme
    Cat.:
    U1930h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat Atrial natriuretic peptide-converting enzyme
    Cat.:
    U1930m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat Atrial natriuretic peptide-converting enzyme
    Cat.:
    P1930Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Atrial natriuretic peptide-converting enzyme
    Cat.:
    P1930Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Atrial natriuretic peptide-converting enzyme
    Cat.:
    P1930Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat Atrial natriuretic peptide-converting enzyme
    Monoclonal Antibody for Rat Atrial natriuretic peptide-converting enzyme
    Monoclonal Antibody for Rat Atrial natriuretic peptide-converting enzyme
    Protein for Rat Atrial natriuretic peptide-converting enzyme
    Protein for Rat Atrial natriuretic peptide-converting enzyme
    Protein for Rat Atrial natriuretic peptide-converting enzyme

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Rat corin gene: molecular cloning and reduced expression in experimental heart failure."
      Langenickel T.H. , Pagel I. , Buttgereit J. , Tenner K. , Lindner M. , Dietz R. , Willenbrock R. , Bader M.
      Am. J. Physiol.287:H1516-H1521(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY;INDUCTION
      strain: Sprague-Dawley.
    2. 2.
      "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
      Gibbs R.A. , Weinstock G.M. , Metzker M.L. , Muzny D.M. , Sodergren E.J. , Scherer S. , Scott G. , Steffen D. , Worley K.C. , Burch P.E. , Okwuonu G. , Hines S. , Lewis L. , Deramo C. , Delgado O. , Dugan-Rocha S. , Miner G. , Morgan M. , more...
      Nature428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: Brown Norway.
    3. 3.
      "Role of glycosylation in corin zymogen activation."
      Liao X. , Wang W. , Chen S. , Wu Q.
      J. Biol. Chem.282:27728-27735(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;ACTIVATION;PROTEOLYTIC PROCESSING;MUTAGENESIS OF ARG-866; ASN-968 AND ASN-1087;GLYCOSYLATION;SUBCELLULAR LOCATION
    4. 4.
      "Decreased renal corin expression contributes to sodium retention in proteinuric kidney diseases."
      Polzin D. , Kaminski H.J. , Kastner C. , Wang W. , Kramer S. , Gambaryan S. , Russwurm M. , Peters H. , Wu Q. , Vandewalle A. , Bachmann S. , Theilig F.
      Kidney Int.78:650-659(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION
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